The majority of males see a progressive decrease in hair growth throughout their lifespan, starting in adolescence and continuing into old age. The degree of hair loss often seen is mostly determined by hereditary factors. 

Follicles exhibit sensitivity to dihydrotestosterone, a male hormone that targets the hair follicles in the frontal hairline and extends to the crown region. Over time, hair development in certain locations diminishes, and the hair shafts progressively become thinner, weaker, and shorter. 

This disorder is referred to as male androgenic alopecia, which is more generally known as male pattern baldness.

Female androgenic alopecia, also known as female pattern baldness, is the most prevalent form of hair loss in women. 

It is a genetically inherited condition that primarily affects the hair follicles in the upper part of the scalp. These follicles are particularly sensitive to the male hormones naturally present in the body. This disorder results in a progressive decrease in hair growth over an extended period of time. 

Various therapeutic interventions can be used to address hair loss, including the administration of bioactive plasma fillers, polynucleotide injection, mesotherapy, microneedling, and the use of bioactive PRF and PRP.